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Canine Autoimmune Hemolytic Anemia (AIHA & IMHA) - Patrice, can yo answer a platelet question?
| Patrice, I was hoping you could educate me on this since I got nowhere with my vet. When Wylie had her relapse on 11/1 her HCT was 27, RBC was 2.93 and her PLT 702, normal range is 120-600 12/6 her HCT was 44 and PLT 532, RBC was 5.03 1/7 HCT is 46 but her PLT jumped back up to 717. Her RBC was 5.12 the only other was sligghtly abnormal was MCH at 29. I am wondering why the spike in the PLT when her HCT looks good. I am assuming even though her PLT is at 717, as on 1/7 she is still in the safe mode since I read somehwere one dogs PLT was liek 3 million. Thanks Laurie |
| Laurie CA |
| Laurie & Patrice, I am also wondering about this, I did ask Dr Dodds, but she might have missed this question in my email. The higher Holly's Hamatocrit goes which currently is 57 the higher her platelet count goes. Which really is not that bad last bloodwork was 496 but up about 50 points from the month before. Linda |
| Linda Sapphire |
| Laurie, There are many many things that can cause this higher than normal number. The most important thing right now is that it isn't a large amount, only a slightly higher number. Purdue University Teaching Hospital reference range for dogs is 200,000-900,000/µl so 717(,000) by their reference is actually not high. Each vendor's equipment has slightly different normal ranges. One cause is a overproduction of platelets by the bone marrow when it is responding to anemia of some kind. Since Wylie had a relapse, we have to assume that there was a great stimulation of the bone marrow to take precursor cells and turn them into red blood cells. But in addition, those cells can also become white blood cells or platelets!! That is the beauty of precursor cells. So it's very possible there has been an over stimulation and the platelets are just responding in general to that. I won't go into other causes right now but I will suggest that during the next blood test you ask your vet to do a blood smear and HAND COUNT the platelets. If the platelets that are being made are a little larger than normal, the automated analyzer may come up with an artificially higher number on the test. So let's figure out first if this slightly higher number is actually true. Then if it is, there are a number of other things that can cause this. my best patrice |
| Patrice NYS |
| Patrice, I am so glad to hear you are on the mend from your accident and on the road to recovery for both you and Chance. I think I mentioned to you my 12 year old lab had a partial torn ACL too, it will be 8 weeks next week. We opted at this time to do the wait and see approach and he is doing quite well, we are keeping our fingers crossed. And Like the other thread, a BIG THANK YOU for all of your valuable time you take out to answer our questions. I will ask at her next test for a smear which is in 2 weeks, and it so good to hear there are different normal ranges. Laurie |
| Laurie CA |
This thread was discussed on 28/02/2009
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