Canine Autoimmune Hemolytic Anemia (AIHA & IMHA) - autoimmune hemolytic anemia caused by Panacur?

My 7 year old Chocolate Lab was treated for giardia with Panacur over a 5 day period. Whithin a week of the end of treatment he acquired autoimmune heolitic anemia. He eventually died after a week long battle. I am wondering if others have experienced autoimmune disorders in their dogs after treatment with Panacur.
brock N. Idaho


Brock,
Oh gosh, this is awful. I am so sorry that this has happened. You must be in shock.

I have done a bit of research and I found an authoritative source that mentions the use of Fenbendazole to treat giardia.
http://www.vin.com/VINDBPub/SearchPB/Proceedings/PR05000/PR00425.htm
"Fenbendazole (Panacur), well known for its effectiveness against a variety of intestinal parasites, also appears to be very effective against Giardia. In a controlled trial at Cornell 6/6 dogs were effectively treated. The same dose that is used to treat roundworms, hookworms, whipworms, and the tapeworm Taenia pisiformis (22 mg/lb orally once daily for 3 consecutive days) is used to treat Giardia. If the infection is not cleared on this regimen, a longer course of therapy is used (5 to 7 days). Fenbendazole has a proven track record for being very safe and is thought to not have any teratogenic effects. Fenbendazole is therefore the drug of choice for treatment of Giardia in pregnant animals."

So they say it is safe to use. However, I also found anecdotal information that this drug can also cause bone marrow failure in some animals.

However, what you are describing to me is a sudden hemolysis, not a slow loss of new blood cells. So I can't be sure that this is exactly what the cause was. I think the dosage you were prescribed might be the clue to this. If the dose was too high, perhaps it could trigger this? Use the recommended dosing above (22 mg/lb orally once daily for 3 consecutive days) to figure out if what you gave is the same.

When you have put some time between your loss, re-visit with your vet and ask them specifically if they feel this could have contributed to this sudden hemolytic anemia.

My sincerest condolence to your family for this very great loss.
patrice
Patrice NYS


Brock,

I have no information to offer you.....but regardless of the reason, I'd like to offer my deepest condolences to you on the passing of your sweet boy. Such a loss is always awful....I recently lost my Bentley to IMHA, and know your grief. I hope you find the answers you need, and that your wonderful memories of your pup will help you through this loss.

Sally and (angel) Bentley
Sally Louisiana


Please accepet my condolences in the loss of your lab. Please know that my thoughts and prayers for strength are with you and your family.

Cheryl & Ginger
Cheryl & Ginger


Brock,
As the caretaker of a sweet 7 year old female yellow Lab, you have my utmost and most sincere condolences. Unfortunately, this is not a one-size-fits all disease with one common cure-all protocol for treatment.

I can only conjecture as to the cause of your Lab's case. I wish that I could provide you with some answers. In any case, my heart goes out to you.

Maggie and Robert
RobertN Superior


Brock,
I am so sorry for your loss. Sometimes you never find out what brought the disease on. I hope that the happier memories with your boy will eventually replace these awful days.
Take care
penny
Penny Lytle Creek


This thread was discussed between 25/11/2011 and 26/11/2011

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