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Canine Autoimmune Hemolytic Anemia (AIHA & IMHA) - Aspirin Survey
| Hello everyone. Another day of worrying I guess. I hope and pray daily for all the dogs affected by this horrible disease. I'ld just like to do a little survey regarding LOW DOSE ASPIRIN. I'm wondering who gives aspirin to their dogs and who doesn't. The doses given (if any), weight of the dog, the meds they're on etc. Add any additional information if you wish. This may help people choose a better coarse of action for their dogs or when talking to their vets regarding aspirin doses. Thanks to all who participate. Thinking of all of you during these tough times, Tessy & Jonathan |
| Jonathan NS |
| jonathan- best that i can remember ive never really gave sway any aspirin |
| josh california |
| We gave Tiggs aspirin until he was in the 'remission' stage (pcv of 37 or higher) because blood clots are one of the leading reasons why dogs with IMHA perish. We had a second opinion at CSU and they concurred through their research that dogs on an ultra low dose had a better shot of getting through the initial crisis on a very low dose. For Tiggs who was about 65lbs,, that was 1/4 of an 80 mg tablet once/day. Hope that helps. melissa and tiggs |
| melissa slc |
| Jonathon You might want to check out this abstract http://www.ncbi.nlm.nih.gov/pubmed/15934255?dopt=Abstract I do have the full article from the JAVMA (Journal of the American Veterinay Medical Association) and it indicates that for this study the ultra low dose of aspirin ws 0.5 mg/kg orally once per day. |
| Joanne MN |
| Just an added note, Jonathan, you might want to check out the Success Stories pages at the Mesiha's Hope Web site http://www.cloudnet.com/~jdickson/successstories.htm since some of these dogs have been on a low dose of aspirin. When my Meisha was diagnosed with AIHA 17 years ago, aspirin was a big NO, NO, it was thought to cause bleeding but now the thinking is that it can perhaps prevent clots. I am reposting here something that I posted about a month ago in regard to clots. Copy and paste starts onw. Each year when I release money from the Meisha’s Hope AIHA/IMHA fund #338 at MAF for a study I have to sign a confidentially agreement that I will not divulge information that I receive about the study until one year after the study has been completed. I receive periodic updates on these studies from time to time as the information becomes available. I received such info at the end of last week on a study that Meisha’s Hope co-sponsored in 2007 which was just completed on 11/30/08. There were 3 pages of very technical information but the following paragraph I am allowed to share with donors. I was also told that the first draft of manuscript is nearing completion and will be submitted to an appropriate veterinary journal in early 2009. Hopefully in the future this will prove to be an effective way to prevent or manage blood clots in AIHA/IMHA dogs. Here is the update I was told I could share with donors and others who are interested. D07CA-303: Pharmacokinetic and Pharmacodynamic Study of Clopidogrel in Dogs UPDATE: Many critically ill dogs are at significant risk for developing blood clots (thromboembolism) that may cause serious complications such as interrupted blood flow to the lungs. Historically drugs such as aspirin and heparin have been used to treat dogs at risk of clotting, but these drugs carry significant risk of bleeding or gastrointestinal complications. In this Morris Animal Foundation/ Meisha’s Hope AIHA/IMHA Fund #338 -funded study, researchers at the University of Georgia investigated the drug, clopidogrel (Plavix®), which decreases the activity of blood platelets. They successfully established that clopidogrel was safe and effective for decreasing platelet activity in dogs. These researchers also created a blood test to evaluate circulating levels of the drug. This test will help to relate the concentrations of drug by-products to the drug effects in the body, and will be a tool for future studies. This study investigated clopidogrel in healthy dogs, so the next step is to apply what they have learned to critically ill dogs. The patients likely to benefit from the clinical effects of clopidogrel are dogs suffering from diseases such as immune-mediated hemolytic anemia.. This project developed a methodology that could also be incorporated into studying the effects of clopidogrel in other species. |
| Joanne MN |
| We never gave Holly any aspirin at any time. She was diagnosed 2 years ago this month, spent 1 week in the hospital, had the bone marrow aspiration done, 1 blood transfusion and started on drugs immediately, which took for her and never any mention of aspirin. Thanks, Linda |
| Linda Sapphire |
| Jonathan, Charlie was diagnosed jan 28th and he was on 20 mg of aspirin until his PCV level stablized at 37. He is now on 20 mg pred and 50 mg azathiaprine and 10mg pepcid he weighs 55 lbs and is 1 yr old. He's doing awesome. we are having his level checked next week. take care Carol |
| Carol Vanc Wa |
| Hi Jonathan...I accidentally put a response for you under my thread....Cody just diagnosed/Tammy |
| Tammy N.J. |
This thread was discussed between 06/03/2009 and 08/03/2009
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