Canine Autoimmune Hemolytic Anemia (AIHA & IMHA) - ? about live vs killed rabies vaccine

I didn't know this existed. I was looking up info from Julies question and found this on a board that is about 3 years old.

Very disturbing to me the link of the 3 year vaccine and cancer. Wylies vet does the 3 year one. But my question is should an AIHA dog or even in remission be getting the live vaccine? Since they are advising people for the flu shots with immune compramized systems not to get the live version. I didnt't think it was because they could get the flu itself but sick in general. Or is it safer the then 3 year and doesn't make at difference whether its live or not? I am going to ask my vet about it the next time I am in

"Most rabies vaccines are given annually, though there are a few that are licensed for 3 years. The hospital where I work used to use the 3 yr vaccine since we originally thought less vaccinating was better, but the 3 yr rabies vaccine is a killed virus, and therefore contains adjuvants to help increase the immune response. These adjuvants in killed vaccines where found to cause a specific type of cancer called a fibrosarcoma - which is extremely fast-growing. The tumors were found to contain an increased amount of aluminum which is from the adjuvant in the vaccine - therefore, the use of adjuvants in vaccines were linked to fibrosarcomas.

Since then, we've switched rabies vaccine products to a recombinant form of live canarypox (not a killed virus) which doesn't contain adjuvants. But this product is only licensed for annual use, not every 3 years. But it's actually safer to use the non-adjuvanted vaccine annually than it is to use the adjuvanted vaccine every 3 years.

Most killed virus vaccines contain adjuvants because a killed virus does not stimulate the immune system very well - which, as we all know, is the whole point of a vaccine. It stimulates an immune response by the body, creating an immunity against that specific virus. So adjuvants are added to create an appropriate immune response by the body to create immunity. Modified live vaccines disable the virus but it's not completely killed, therefore some of these vaccines do not contain adjuvants, but the risk of actually causing the disease you are vaccinating for is increasing, but still rare"

Laurie CA


Hi Laurie,

I don't know an answer for your question...but after my experiences I would never again vaccinate a dog who had AIHA, or any reactions similar to what my dog has had.

The fibrosarcoma thing, from what I have read is mostly in cats, but it does rarely happen in dogs too. I have never heard that the 3 year was more dangerous on this point. From what I have read the 3 year vaccine is exactly the same as the 1 year, but the companies mark it as a 3 year to appease the Counties. This is just what i have found in my research, I really can't say for sure.
Julie IL


Julie, looks like you are right and thats what I thought. Looks like canine rabies is only the killed version, I thought they were talking about dogs.

I have to get Wylies rabies vaccine because we live in a rural area and she actually got attacked by coyotes a few years ago. But I dont do any other vaccines.

Was your dog vaccinated for Lepto? Or the I think its called the 7 in one shot? With 7 vaccines in one?

That one can have some serious side effects and lumping them all together is not good at all. I was wondering if thats a possiblity for cause of seizures

Laurie
Laurie CA


Hi Laurie,

No we don't do Lepto... but they did get their rabies and DA2PPV. I will never give any vaccines together again. The DA2PPV is possibly what caused some of Hurleys problems, we will just never be sure, and I am not taking any more chances.

Julie IL


This thread was discussed between 19/10/2009 and 20/10/2009

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